Games
| date | competition | season | team | score | team | venue | referee | attendance | sources |
|---|---|---|---|---|---|---|---|---|---|
| Oct. 23, 2021 | MLS | 2021 | Seattle Sounders | 1 - 2 | Sporting Kansas City | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | Columbus Crew | 1 - 2 | New York Red Bulls | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | D.C. United | 0 - 6 | New York City FC | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | Nashville SC | 0 - 1 | Philadelphia Union | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | Montreal Impact | 1 - 1 | Toronto FC | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | Chicago Fire | 1 - 0 | Real Salt Lake | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | FC Cincinnati | 1 - 5 | Inter Miami | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | Los Angeles FC | 1 - 1 | Minnesota United FC | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | Colorado Rapids | 2 - 0 | Portland Timbers | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | FC Dallas | 2 - 2 | LA Galaxy | — | 1 | ||
| Oct. 23, 2021 | MLS | 2021 | San Jose Earthquakes | 1 - 1 | Vancouver Whitecaps | — | 1 |
Standings
| team | competition | season | GP | W | T | L | gf | ga | gf/ga |
|---|---|---|---|---|---|---|---|---|---|
| Seattle Sounders | MLS | 2021 | 31 | 17 | 7 | 7 | 51 | 28 | 1.82 |
| Sporting Kansas City | MLS | 2021 | 30 | 16 | 7 | 7 | 54 | 34 | 1.59 |
| Colorado Rapids | MLS | 2021 | 31 | 15 | 10 | 6 | 45 | 32 | 1.41 |
| Portland Timbers | MLS | 2021 | 31 | 14 | 4 | 13 | 48 | 51 | 0.94 |
| LA Galaxy | MLS | 2021 | 31 | 13 | 7 | 11 | 46 | 48 | 0.96 |
| Philadelphia Union | MLS | 2021 | 31 | 13 | 10 | 8 | 43 | 32 | 1.34 |
| D.C. United | MLS | 2021 | 31 | 12 | 5 | 14 | 51 | 50 | 1.02 |
| Minnesota United FC | MLS | 2021 | 31 | 12 | 9 | 10 | 36 | 38 | 0.95 |
| New York City FC | MLS | 2021 | 31 | 12 | 8 | 11 | 51 | 34 | 1.50 |
| New York Red Bulls | MLS | 2021 | 30 | 12 | 7 | 11 | 37 | 31 | 1.19 |
| Real Salt Lake | MLS | 2021 | 30 | 12 | 6 | 12 | 48 | 46 | 1.04 |
| Inter Miami | MLS | 2021 | 31 | 11 | 5 | 15 | 33 | 48 | 0.69 |
| Los Angeles FC | MLS | 2021 | 31 | 11 | 8 | 12 | 47 | 45 | 1.04 |
| Montreal Impact | MLS | 2021 | 31 | 11 | 10 | 10 | 44 | 41 | 1.07 |
| Nashville SC | MLS | 2021 | 31 | 11 | 16 | 4 | 47 | 28 | 1.68 |
| Vancouver Whitecaps | MLS | 2021 | 31 | 11 | 11 | 9 | 41 | 42 | 0.98 |
| Columbus Crew | MLS | 2021 | 31 | 10 | 8 | 13 | 38 | 42 | 0.90 |
| Chicago Fire | MLS | 2021 | 32 | 9 | 7 | 16 | 36 | 51 | 0.71 |
| San Jose Earthquakes | MLS | 2021 | 31 | 9 | 10 | 12 | 41 | 48 | 0.85 |
| FC Dallas | MLS | 2021 | 31 | 6 | 11 | 14 | 43 | 52 | 0.83 |
| Toronto FC | MLS | 2021 | 31 | 6 | 8 | 17 | 35 | 60 | 0.58 |
| FC Cincinnati | MLS | 2021 | 31 | 4 | 8 | 19 | 33 | 64 | 0.52 |