| April 5, 2022 |
USOC |
2022 |
2 |
Central Valley Fuego FC |
4 - 1 |
El Paso Locomotive |
Lamonica Stadium (Clovis H.S.) |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
Charlotte Independence |
2 - 4 |
North Carolina Fusion U23 |
American Legion Memorial Stad… |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
Detroit City FC |
3 - 0 |
Michigan Stars FC |
Keyworth Stadium |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
FC Tulsa |
2 - 1 |
Tulsa Athletic |
ONEOK Field |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
Indy Eleven |
0 - 2 |
St. Louis City 2 |
Indianapolis, IN |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
Las Vegas Legends FC |
0 - 5 |
New Mexico United |
Univ. of New Mexico Soccer Complex |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
LA Force |
2 - 5 |
Orange County SC |
Orange County Great Park (Championship Stadium) |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
Maryland Bobcats FC |
0 - 2 |
Pittsburgh Riverhounds |
Highmark Stadium |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
D'Feeters Kicks SC |
1 - 3 |
San Antonio FC |
Toyota Field |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
Tampa Bay Rowdies |
6 - 0 |
The Villages SC |
Progress Energy Park |
|
— |
0 |
| April 5, 2022 |
USOC |
2022 |
2 |
Des Moines Menace |
1 - 2 |
Union Omaha |
Morrison Stadium (Creighton Univ.) |
|
— |
0 |