Games
| date | season | round | team | score | team | venue | referee | attendance | sources |
|---|---|---|---|---|---|---|---|---|---|
| Sept. 16, 2021 | 2021 | sf | CF Monterrey | 4 - 1 | Cruz Azul | Estadio Azul | — | 1 | |
| Aug. 11, 2021 | 2021 | sf | CF Monterrey | 1 - 0 | Cruz Azul | Estadio Tecnológico | — | 1 | |
| May 4, 2021 | 2021 | qf | Cruz Azul | 1 - 0 | Toronto FC | Estadio Azul | — | 1 | |
| April 27, 2021 | 2021 | qf | Cruz Azul | 3 - 1 | Toronto FC | BMO Field | — | 1 | |
| April 13, 2021 | 2021 | /16 | Arcahaie FC | 0 - 8 | Cruz Azul | Estadio Azul | — | 1 | |
| April 6, 2021 | 2021 | /16 | Arcahaie FC | 0 - 0 | Cruz Azul | Arcahaie, Haiti | — | 1 |