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Oct. 30, 2008 2008 qf Chicago Fire 0 - 0 New England Revolution Gillette Stadium Alex Prus 5221 0
Nov. 1, 2008 2008 qf Houston Dynamo 1 - 1 New York Red Bulls Giants Stadium Kevin Stott 11578 0
Nov. 1, 2008 2008 qf Columbus Crew 1 - 1 Kansas City Wizards CommunityAmerica Ballpark Jorge González 10385 0
Nov. 1, 2008 2008 qf Chivas USA 0 - 1 Real Salt Lake Rio Tinto Stadium Ricardo Salazar 14719 0
Nov. 6, 2008 2008 qf Chicago Fire 3 - 0 New England Revolution Toyota Park Jair Marrufo 17312 0
Nov. 8, 2008 2008 qf Columbus Crew 2 - 0 Kansas City Wizards Crew Stadium Ricardo Salazar 11153 0
Nov. 8, 2008 2008 qf Chivas USA 2 - 2 Real Salt Lake StubHub Center Michael Kennedy 19256 0
Nov. 9, 2008 2008 qf Houston Dynamo 0 - 3 New York Red Bulls Robertson Stadium Baldomero Toledo 30053 0
Nov. 13, 2008 2008 sf Chicago Fire 1 - 2 Columbus Crew Crew Stadium Terry Vaughn 14688 0
Nov. 15, 2008 2008 sf New York Red Bulls 1 - 0 Real Salt Lake Rio Tinto Stadium Jair Marrufo 20008 0
Nov. 23, 2008 2008 Columbus Crew 3 - 1 New York Red Bulls StubHub Center Baldomero Toledo 27000 0